I am 32 weeks pregnant and have been taking 400 mg of the drug for several months because of an autoimmune disease. My doctor has suggested that it may not be safe for me to breastfeed because I will need to remain on the drug after I deliver. Chloroquine therapeutic class Plaquenil moon face Drug interaction of chloroquine Is hydroxychloroquine Plaquenil safe to take if I'm pregnant or breastfeeding? Hydroxychloroquine should only be used in pregnant women for malaria prophylaxis or treatment. Hydroxychloroquine may be secreted in breast milk and may cause side effects in the infant. The vision of the InfantRisk Center is to create a new body of drug information concerning the safety of medications and their use during pregnancy and lactation. Additionally, the center will expand, enhance and disseminate knowledge regarding the use of medications and other environmental chemicals by pregnant and breastfeeding women worldwide. Experts say pregnant women can safely take the steroid prednisone during the second and third trimester of pregnancy and while breastfeeding. Experts also consider Plaquenil hydroxychloroquine. Obviously I have to discuss this in more detail with my doctor and pediatrician, but was curious if there is anyone out there. There contradictory reports online - some saying there are no effects and others saying it is not safe. Is hydroxychloroquine safe to take while breastfeeding Hydroxychloroquine MedlinePlus Drug Information, InfantRisk Center Plaquenil and lymphomaCan plaquenil cause joint painDifference between methotrexate and plaquenilIs plaquenil safe to use The most common of these is Plaquenil hydroxychloroquine, which the AAP has approved for use in breastfeeding mothers. Steroids. Steroids are used to control inflammation, and suppress an over-active immune system. The most common of these is prednisone. Large doses may be used during life-threatening episodes. Arthritis, Fibromyalgia and Breastfeeding - Safe Motherhood. How Rheumatoid Arthritis Affects Pregnancy. Plaquenil and Breastfeeding - eMedTV Health Information.. Breastfeeding. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Drug Interactions Hydroxychloroquine is a foundation of SLE treatment. A recently published study from China reported on 33 women who had been taking hydroxychloroquine sulfate for at least 1 year and were exclusively breastfeeding. They had hydroxychloroquine levels in milk determined five times during a 12-hour period just before and after a dose. Chloroquine or hydroxychloroquine. No harmful effects on the fetus have been observed when chloroquine or hydroxychloroquine are used in the recommended doses for malaria prophylaxis. 2 Observational data 5, 6 amounting to more than 1000 exposures and 1 double-blind randomized-controlled trial 7 N = 951 have evaluated the use of chloroquine at various stages of pregnancy for the prevention.