It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Can sulfasalazine and plaquenil be taken together Side effect plaquenil eyes Medicines and the Digestive System. Medicines taken by mouth can affect the digestive system in a number of different ways. Both prescription and over-the-counter medicines, while usually safe and effective, may create harmful effects in some people. Certain medicines taken together may interact and cause harmful side effects. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Stomach digestion meditcation plaquenil Lupus Board Index Plaquenil and stomach issues., Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil law suits But stomach problems seem to be directly related to how sjogrens affects me anyway. I think it's ironic that the routine medication for it also can cause stomach issues. Nevertheless, I decided the stomach pain was more than I could live with and I really could not tell a significant difference in inflammation reduction when I was taking it. Plaquenil/Hydroxychloroquine and stomach problems?. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical.. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Hydroxychloroquine is a prescription drug. It comes as an oral tablet. Hydroxychloroquine is available as the brand-name drug Plaquenil. It’s also available in a generic version. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can.