Antimalarials are usually given as one or two pills, once a day. Side effects include vision changes (blurring, halos around lights and sensitivity to light), headache, dizziness, nausea and vomiting. Individuals taking an antimalarial should have eye examinations periodically. Plaquenil allergic reaction rash Plaquenil side effecs Exacerbation of Psoriasis due to Hydroxychloroquine Sara S McCoy1*, Vivek Nagaraja2, Scott Paviol3, Johann E Gudjonsson4 and J Michelle Kahlenberg1 1 Department of Internal Medicine, Di-vision of Rheumatology, University of Michigan, USA 2 Department of Internal Medicine, Division of Rheumatology, University of Toledo, USA Disease-modifying antirheumatic drugs. Unless you are directed to do so by your doctor, do not take Plaquenil, the most commonly prescribed antimalarial. The use of Plaquenil may cause a severe flare of psoriasis. Some antimalarials can cause the skin disease to get worse in some individuals. Talk to your doctor about the available. Interest in hydroxychloroquine treatment of psoriatic arthritis has been revived because of recent series found no exacerbation of psoriatic skin lesions in 50 psoriatic arthropathy patients treated with hydroxychloroquine. A psoriatic arthropathy patient whose skin lesions were markedly exacerbated by hydroxychloroquine is reported. The use of Plaquenil may cause a severe flare of psoriasis. Unless you are directed to do so by your doctor, do not take Plaquenil, the most commonly prescribed antimalarial. Hydroxychloroquine psoriasis Hydroxychloroquine Oral Route Before Using - Mayo Clinic, DMARDs & Psoriatic Arthritis National Psoriasis Foundation Hydroxy chloroquine oral or sulfatePlaquenil for chronic lymeChloroquine mechanism of action iodineLysosome chloroquinePlaquenil and breastfeeding lupus Psoriasis is an autoimmune skin disease characterized by the spontaneous appearance of symptoms, followed by periods of causes itchy or painful patches of skin that are thick, red, and have silvery scales. Drugs That Can Trigger Psoriasis Flares. Hydroxychloroquine in psoriatic arthropathy exacerbations.. Psoriasis Causes & Triggers National Psoriasis Foundation. Tell your doctor if you have or have ever had liver disease, psoriasis, porphyria or other blood disorders, G-6-PD deficiency, dermatitis skin inflammations, or if you drink large amounts of alcohol. tell your doctor if you have ever had vision changes while taking hydroxychloroquine, chloroquine Aralen, or primaquine. Hydroxychloroquine may worsen psoriasis. SLIDESHOW Rheumatoid Arthritis RA Symptoms & Treatment See Slideshow. What is the dosage for hydroxychloroquine Plaquenil? The usual adult dose for treating malaria is 800 mg initially, followed by 400 mg 6-8 hours later and then 400 mg at 24 hours and 48 hours. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. Hydroxychloroquine is rapidly absorbed from the gastrointestinal tract, and steady-state concentrations are reached after 4–6 weeks; 45% of hydroxychloroquine binds to plasma proteins that are deposited in tissues such as the liver, spleen, kidney, and lung.