Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Chloroquine phosphate and pregnancy Plaquenil 200 in pregnancy Infections should receive chloroquine prophylaxis 300 mg base po once a week during pregnancy. After delivery, patients with normal G6PD activity should be treated with primaquine or tafenoquine or continue with chloroquine prophylaxis for a total of 1 year. In Myanmar, the reported numbers of confirmed malaria cases at outpatient departments were 649522 in 2010, 533720 in 2071 in 2013; whereas reported numbers of in patients were 43602 in 2010, 33732 in 202 in 2013. Reported malaria deaths were 788 in 2010, 581 in 2011, and 236 in 2013. Spread of artemisinin-resistant Plasmodium falciparum in Myanmar a cross-sectional survey of the K13 molecular marker February 21, 2015 By Leave a Comment Emergence of artemisinin resistance in southeast Asia poses a serious threat to the global control of Plasmodium falciparum malaria. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine resistance in myanmar Epidemiology of malaria and chloroquine resistance in Mizoram., Guidelines For Malaria Diagnosis And Treatment In Myanmar Ewg pesticide epa chloroquine South East Asia has been implicated in the rise of resistance to both chloroquine and artemisinin. The main explanation is that lower levels of natural malaria immunity exist in the region than in Africa. With no background resistance, the drugs have to do all the work in infected patients in South East Asia. Malaria on Myanmar-India border is 'huge threat' - BBC News. Myanmar –. Border Malaria Associated with Multidrug Resistance on Thailand-Myanmar.. All the chloroquine-resistant cases were again treated with chloroquine 1500 mg and no further recrudescence or relapse was detected on days 21 and 28. This study indicates that chloroquine is losing its efficacy against P. vivax in Myanmar. The team of researchers, led by Drs Kyaw Myo Tun and Charles Woodrow, confirm that resistance is established in western Myanmar toward the border with India. The potential spread of artemisinin resistance – the most widely used drug against malaria infection – further westward poses a serious threat to global control of malaria. DRUG RESISTANT MALARIA Chloroquine resistance Chloroquine is ineffective in almost all malaria endemic countries In India chloroquine resistance was first detected in 1973 in Assam. Severe in northeast and southeastern regions of India with high morbidity and mortality.