The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased tears and saliva. Your immune system mistakenly attacks your body's own cells and tissues. Aralen dosis Plaquenil for fibromyalgia reviews Sjogren’s syndrome may also be confused with diseases, such as viral infections drug side effects e.g. antihypertensives, antidepressant or antihistamines. Other diseases may also cause salivary gland enlargement, such as viral infections, sarcoidosis a chronic lung disease, and diabetes. Rheumatologists love to prescribe plaquenil for people who have either Sjogren's, or Lupus. It is apparently kind of a wonder-drug for Lupus, in that it actually prevents flares in the majority, or a large percentage, of people. It doesn't do that for Sjogren's, but they don't know what it does do, so they like to give it to you and see what. Although there are few reports that describe the efficacy of hydroxychloroquine for skin disease in Sjögren syndrome, hydroxychloroquine is widely used in the treatment of autoimmune skin diseases such as cutaneous lupus erythematosus. Certain genes put people at higher risk of the disorder, but it appears that a triggering mechanism — such as infection with a particular virus or strain of bacteria — is also necessary. Scientists aren't certain why some people develop Sjogren's syndrome. Plaquenil and sjogren's syndrome New Treatment Guidelines for SjOgren's Disease, Hydroxychloroquine? - Symptoms and Medical Treatments. Macular oct changes in plaquenil toxicity Importance Primary Sjögren syndrome is a systemic autoimmune disease characterized by mouth and eye dryness, pain, and fatigue. Hydroxychloroquine is the most frequently prescribed immunosuppressant for the syndrome. However, evidence regarding its efficacy is limited. Hydroxychloroquine for Sjögren Syndrome Symptoms. Cutaneous purpura of Sjögren syndrome successfully treated.. Sjogrens Mayo Clinic Connect. User Reviews for Plaquenil to treat Sjogren's Syndrome. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. The Sjogren’s Syndrome Foundation has issued the first-ever treatment guidelines for systemic Sjogren’s syndrome, a disease that affects as many as 6 million people in the U. S. with or without connective tissue disease. Hydroxychloroquine Plaquenil, an antimalarial drug used in lupus and rheumatoid arthritis, may be helpful in some patients with Sjögren's syndrome by reducing joint pain and rash experienced by some patients.