According to legend it was first brought to Europe by a Countess who had been treated with it in Peru in the 1600s. In 1820, two French chemists isolated quinine from the cinchona bark and quinine became a treatment of reference for intermittent fever throughout the world. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance. Stop hair loss plaquenil Hydroxychloroquine pruritus Plaquenil mayo clinic Drug resistance in malaria Umar Farooq & R. C. Mahajan Department of Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India Ever since the discovery of the first case of chloroquine resistance along the Thai-Combodian border DRUG RESISTANT MALARIA Chloroquine resistance Chloroquine is ineffective in almost all malaria endemic countries In India chloroquine resistance was first detected in 1973 in Assam. Severe in northeast and southeastern regions of India with high morbidity and mortality. Mizoram, a northeastern state in India, shares international borders with Myanmar and Bangladesh and is considered to be one of the key routes through which drug-resistant parasites of Southeast Asia enter mainland India. Despite its strategic location and importance, malaria epidemiology and molecular status of chloroquine resistance had not been well documented, and since chloroquine CQ. These compounds belonged to a new class of antimalarials, the four-amino quinolines. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin (chloroquine) and Sontochin (3-methyl-chloroquine). Chloroquine resistance india Chloroquine Oral Uses, Side Effects, Interactions, Pictures., DRUG RESISTANT MALARIA CURRENT STATUS Plaquenil and dermatomyositisChloroquine mechanism of action iodine In India, 12‐15 million new cases of Plasmodium vivax occur each year. These cases are successfully treated with 600 mg chloroquine adult dose. We report the results of malaria treatment of a 13‐. Chloroquine resistant Plasmodium vivax malaria in India - Dua - 1996.. Epidemiology of malaria and chloroquine resistance in Mizoram.. Antimalarial drug resistance of Plasmodium falciparum in India changes.. Chloroquine was being used in many areas during the study period. Earlier also, chloroquine resistance was shown by therapeutic efficacy studies, and India switched over to ACT for falciparum malaria all over the country 21. To conclude, the study showed high levels of resistance to chloroquine; and also to monodesethylamodiaquine. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat.