When I do sleep, upon waking it feels like I never slept. Is this a common side effect and will it subside with time? Plaquenil treatment Fda plaquenil 98 hydroxychloroquine Hydroxychloroquine drug card Dec 15, 2010 now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works. i'm not expecting it to work over night but soon hopefully i am still in so much pain everyday and hoping for some relieve soon. What should I avoid while taking Plaquenil? Avoid taking an antacid or Kaopectate kaolin-pectin within 4 hours before or after you take hydroxychloroquine. Some antacids can make it harder for your body to absorb hydroxychloroquine. Plaquenil side effects Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Hello I have just been reading that plaquenil can cause insomnia and nightmares which I suffer with. Ive helped x Never taken mine at night so can't comment on that. I read the insert that came with the prescription and it didn't mention insomnia. Can i take plaquenil at night Immune & Autoimmune - Lupus don't want to take plaquenil anymore, Plaquenil Uses, Dosage & Side Effects - Hydroxychloroquine sulphate 200mgDoes hydroxychloroquine affect osseointegrationHydroxychloroquine mfg by mylan Stars. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Plaquenil Side Effects Go Away? DailyStrength. Take Plaquenil exactly as prescribed. Plaquenil comes in tablet form. It is taken once or twice a day, unless it is used for the prevention of malaria, in which case it is taken once a week beginning 1 to 2 weeks prior to traveling to an area where malaria is common. Take this medication with a meal or a glass of milk to prevent stomach upset. Plaquenil doesn't usually cause insomnia. It is most likely something else, such as prednisone if you're taking it or anxiety. Insomnia is a common complaint for people with Lupus, some as a result of the steroids and some from general stress of the disease. Lupus is a difficult diagnosis to handle and can really make it difficult to fall asleep. I started plaquenil 200mg in the morning with breakfast and 200mg at night. My side effects were loss of appetite and nervousness/jittery, like anxiety. My side effects resolved after a few weeks. These days I tolerate plaq so well that I take 400mg once a day at night now. It's a great drug if you can work through the initial side effects.