So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Chloroquine side effect Does plaquenil cause blindness Because previous studies have found strong connections between Plaquenil and decreased lupus flares, the amount of damage to the body, and the favorable impact on survival, the researchers deemed it to be unethical to conduct a double-blind, placebo study. Instead, the researchers used statistical models to create two groups based on the. Several risk factors may increase the likelihood of retinal toxicity from Plaquenil such as, age of greater than 60 years, daily dose more than 6.5 mg/kg; use of the drug more than 5 years, obesity, preexisting retinal disease and, renal or liver failure. The incidence of new-onset or flaring psoriasis associated with Plaquenil varies from 0-100% depending on which case series report you read! Allergic and psoriasis-like rashes tend to develop within the first few weeks or months of starting Plaquenil. If Plaquenil helps a serious chronic disease such as lupus, it may be taken for years. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Chances of having a lupus flare when stopping plaquenil Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, The Risk of Retinal Toxicity with Plaquenil Plaquenil givimg me sore throatHydroxychloroquine and neuropathyAdverse effects of plaquenil Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Stopping plaquenil. DailyStrength. Plaquenil Use in Autoimmune Diseases. Lupus Flares Recognizing one, triggers, and prevention.. However, if you can be vigilant and be aware of such signs and symptoms of Lupus flare, you can potentially prevent a full fledged flare. Lupus Flare – signs and symptoms Aching or increased swelling of the joints; Weakness and pain of the muscles; Unusual fevers; Unusual exhaustion and/or fatigue; Hair loss; Dizziness and difficulty with focus and memory; Digestive Problems; Rash; Swollen Lymph Glands; You can find more information on other Lupus Symptoms here. Here are some things that may reduce the risk of both the onset of lupus, in those who are at risk, and a flare-up. Hydroxychloroquine Plaquenil This is an antimalarial drug. It can help to. Plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under control. This drug is also effective at preventing lupus flares.