It calms your immune system and blocks the functioning of parasites responsible for malaria. I have never been told exactly what Plaquenil does for SLE. I stopped going to him because he was so negative and I lost an entire year with my family and friends because I was scared to death that being outside in the heat or cold would make me worse. Effects of plaquenil on skin Chloroquine prophylactic therapy All information provided on this website is provided on a educational and informational purposes only. It is not intended as a substitute for your healthcare professional or physician. Jun 15, 2009 Systemic lupus erythematosus SLE is an autoimmune disorder that can affect multiple organs with varying degrees of severity. Renal involvement in SLE can range from silent disease to severe renal insufficiency occurring in 50-70% of lupus patients depending on the population studied 1-3. Despite advances in therapy, the morbidity and. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. I am doing very well but I want to know more about what Plaquenil actually does for SLE. Ok to go in the heat just wear lot s of suncreen and a hat. Cold is no problem usually covered with alot of warm clothes anyway... My family doctor prescribes my medicine now and I only go to the Rheumatologist if I have a flare. Plaquenil for lupus review alkaline Plaquenil oral Reviews and User Ratings Effectiveness., Protective Effect of Hydroxychloroquine on Renal Damage in. Plaquenil increase liver enzymesPlaquenil and log qt200 mg plaquenil Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. Hydroxychloroquine Plaquenil. Stopping plaquenil. DailyStrength. Plaquenil - Complete Drug Information, Side Effects and.. I was diagnosed with Tumid Lupus which causes raised red ulcer looking rash mainly on my face but can be anywhere on the body. it is cutaneous not systemic. I also have osteoarthritis. I started on Plaquenil in 2015 200 mg then increased to 400 mg after 3 months. It took many months for the ulcer like spots to go away but the drug works. These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Lupus is a chronic inflammatory autoimmune disease with a wide range of clinical presentations resulting from its effect on multiple organ systems. There are four main types of lupus neonatal, discoid, drug-induced, and systemic lupus erythematosus SLE, the type that affects the majority of patients.