They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Icd-10 code plaquenil Can you take diet pills with plaquenil Can you donate blood if you are on plaquenil Plaquenil 200 mg bid Yes Rituximab rituxin is a monoclonal antibody to cd20 an antigen located on lymphocytes. One consequence of using this drug is a drop in lymphocyte numbers bad cells and good cells. This decline lowers the effectiveness of the immune system for a period of time. If Plaquenil helps, then maybe it is reining the immune system in I don't actually know how it works scientifically. Theoretically, it may make us more vulnerable to external viruses. Also, about having colds and lupus symptoms; I know it's not everyone's experience, but whenever I have a cold, I have fewer lupus symptoms. My Rheumatologist told me that it doesn't suppress your immune system. If you're on steroids, Methotrexate, Enbrel, or similar drugs then they will suppress your immune system. Hope this helps and best of luck! It's a tough disease but you WILL improve. It just takes time. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. Does hydroxychloroquine lower your immune system Hydroxychloroquine Plaquenil, Hydroxychloroquine and the Immune System Lupus Forums at. Can hydroxychloroquine sulfate get you highWhat does the plaquenil test consist of Howdy LadyDi, sorry you are having problems. Plaquenil is what is call an immune modifier. It is not a immune suppressant. Originally it was used to prevent Malaria. Then it was discovered to be effective for the treatment of Lupus. Plaquenil has the least amount of side affects in treating auto immune disorders. Does Plaquenil supress the immune system?. I have been taking plaquenil for almost a year, does this.. Plaquenil and lowered immune system - Sjogren's World. The answer was that while Hydroxychloroquine, the generic name for Plaquenil and the tablet I take in the same dose as yourself i.e. 200mg a day at the moment, is a disease modifying drug and an anti-malarial, it is also a mild immunosuppressant too. So this could be why your immune system is so low at the moment. However, it’s believed that this drug affects how your immune system works, which may be a benefit in lupus erythematosus and rheumatoid arthritis. Hydroxychloroquine side effects According to the American College of Rheumatology, hydroxychloroquine Plaquenil, is a “disease-modifying anti-rheumatic drug DMARD,” meaning that it helps reduce the pain and swelling that come with arthritis. It can also reduce the incidence of joint damage, thus lessening the risk of developing a long-term disability from complications of RA.