It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine pigmentation histology Plaquenil 200 mg efectos secundarios Oct 15, 2012 The way it was explained to me is that Plaquenil is not an immunosuppresant, but is used because of its anti-inflammatory effect, so it alone should not lower your ability to fight infections. Mar 23, 2014 Plaquenil is not thought to have a strong effect on the immune system with regard to illnesses etc.far as I am aware. I am sure others will be on to share any similar experiences however, I found the plaquenil, if anything very weak for my MCTD.needed steroids too whilst it was kicking in.then Cellcept etc etc Howdy LadyDi, sorry you are having problems. Plaquenil is what is call an immune modifier. It is not a immune suppressant. Originally it was used to prevent Malaria. Then it was discovered to be effective for the treatment of Lupus. Plaquenil has the least amount of side affects in treating auto immune disorders. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Does plaquenil lower your immune system Weakened immune system? DailyStrength, Plaquenil and immune system Lupus Forums at The Lupus Site Discoid lupus and plaquenil Plaquenil itself probably does not have a direct affect on your immune system - it is a DMARD and is not considered to be an immunosuppressant. However, many with active autoimmune diseases feel that they are not succeptible to many of the common viruses that they are exposed to - somewhat of a silver lining. Anyone on Hydroxychloroquine plaquenil - Autoimmune.. Does Plaquenil supress the immune system?. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory pathways. Does that mean I have a suppressed immune system. REFILL YOUR PLAQUENIL NOW. DO NOT STOP OR REDUCE YOUR MEDICATIONS without direction from a medical professional. In many viral infections IT IS YOUR OWN IMMUNE RESPONSE THAT KILLS YOU or put you at high risk. Do not assume that stopping your medication will make you safer. Jun 13, 2019 Plaquenil lowers your immune system’s ability to cause inflammation. This can help control symptoms like rashes, skin and mouth sores and joint pain. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss.