Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. Plaquenil vaccines Plaquenil retinopathy to reverse Aug 27, 2018 Glioblastoma is one of the most aggressive human cancers shown to have a better response to standard therapy when combined with chloroquine. While there is considerable evidence for the efficacy and safety of chloroquine as an adjuvant treatment for cancer, the mechanisms underlying the tumor suppressive actions of this drug remain elusive. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Jul 30, 2019 Symptoms of Overdose. Some side effects of chloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Using chloroquine to treat glioblastoma This Malaria Drug Is Having an Amazing Effect on Brain Cancer., Chloroquine Oral Uses, Side Effects, Interactions. Plaquenil side effects with anti depressantsBest price for plaquenilCan hydroxychloroquine cause dry eyes Nov 28, 2017 Chloroquine and related antimalarial drugs. This class of drugs has been widely used for decades in malaria prevention and therapy. These molecules are effective in blocking P. falciparum life cycle and are relatively well-tolerated. Recently, antimalarial drugs are also considered in cancer chemotherapy 84. Drug repurposing for the treatment of glioblastoma multiforme.. Chloroquine Side Effects Common, Severe, Long Term -. Kristen's Natural Treatment Plan for Aggressive Brain.. Interesting clinical data have emerged about clinical experience with chloroquine as adjuvant therapy for patients with glioblastoma multiforme GBM. Chloroquine has the potential of opening new frontiers in the treatment of glial neoplasms and should be tested in large clinical trials. Finally, the blood-brain barrier presents a challenge to glioblastoma treatment and was once believed to prevent immune cells in the bloodstream from reaching the brain. However, research at MD Anderson and elsewhere has shown that such immune cells do indeed reach brain tumors, making immunotherapy an option. The anti-malaria drug chloroquine has now been used as a last resort on three brain cancer patients, and in each case, it seems to have overcome the cancer's resistance to traditional treatments. Chloroquine appears to break down the defences that tumours develop in response to cancer-fighting drugs by effectively 'resetting' their vulnerability to treatment.