It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Half life of hydroxychloroquine sulfate Chloroquine autophagy inhibitor Introduction. Juvenile idiopathic arthritis JIA is a chronic inflammatory disease of unknown etiology. JIA is defined by the International League of Associations for Rheumatology ILAR as arthritis that begins before the age of 16 and persists for at least 6 weeks with exclusion of other known conditions. Facts for patients and caregivers about the DMARD drug Hydroxychloroquine Plaquenil such as usages, Today, it is used to treat rheumatoid arthritis, Discover the 5 Common Signs and Symptoms of Rheumatoid Arthritis. A SINGLE injection could provide months of relief for rheumatoid. arthritis – with mixed results. I have a mild form of rheumatoid arthritis serum positive, treated with Plaquinel 400mg daily and Naproxan 1000mg daily for the past 6 years. I have had no problems with the arthritis in all that time and still don't. My question is about the Plaquinel. This summer I started having skin discoloration on the top of both of my feet. The color of my skin turned a deep blackish blue color. Could. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Plaquenil and juvenile arthritis blue fingers How long did Plaquenil/Hydroxychloroquine take., How Does Plaquenil Work For Rheumatoid Arthritis Can plaquenil cause extreme fatigueHydroxychloroquine dose malariaHydroxychloroquine sulphate tablets usesHydroxychloroquine will it help ringwormMalaria chloroquine Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed. Taking Plaquenil for Rheumatoid Arthritis. Skin Discoloration and Plaquenil • Johns Hopkins Arthritis.. RA and Hydroxychloroquine How Effective is it for.. The symptoms of rheumatoid arthritis RA typically affect the hands, wrists, and feet. Spotting signs of RA early could lead to an early diagnosis and appropriate treatment. Early and consistent. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 A rare complication of the commonly used rheumatoid arthritis drug hydroxychloroquine Plaquenil is injury to the retina the light-sensing portion of the back of the eye. The earliest sign of retinal changes from hydroxychloroquine is a decreased ability to distinguish between red and green colors.