Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil makes my body ache Plaquenil acute pancreatitis Plaquenil is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay. Chloroquine A 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. The key treatments for asthma are steroids and other anti-inflammatory drugs. These asthma drugs both help to control asthma and prevent asthma attacks. Steroids and other anti-inflammatory drugs. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Chloroquine as antiinflammatory Anti-inflammatory activity of chloroquine and amodiaquine., Definition of chloroquine - NCI Drug Dictionary - National. Plaquenil stomach ulcerChloroquine endosomal escape mechanismPlaquenil and heartSpectral-domain optical coherence tomography in hydroxychloroquine retinopathyPlaquenil and detached retina Mechanism of action of hydroxychloroquine as an antirheumatic drug. Fox RI1. Author information 1Department of Rheumatology, Scripps Clinic and Research Foundation, La Jolla, CA 92037. The antimalarial agents chloroquine and hydroxychloroquine have been used widely for the treatment of rheumatoid arthritis and systemic lupus erythematosus. Mechanism of action of hydroxychloroquine as an antirheumatic drug.. Asthma, Steroids, and Other Anti-Inflammatory Drugs. Pharmacology Anti-inflammatory and Antineoplastic Drugs 25.. Chloroquine comes as a tablet, liquid, or injection. Your dose will depend on your medical condition, age, weight, and response to treatment. You can take this medicine with food if it causes an. Facts for patients and caregivers about the DMARD drug Hydroxychloroquine Plaquenil such as usages, common dosages, safety tips and side effects. Chloroquine is sometimes tolerated by patients who do not tolerate hydroxychloroquine. Ophthalmologic retinal and visual field testing should be performed at baseline or soon after drug initiation and then at 6 -12 month intervals.