Sorry, there has been an issue processing your request. Alternatively, head back to the home page and see how we're leading the fight against the pain of Arthritis. Hello hope everyone is welljust a quick question, i have been on methotrexate for 2 months increasing from 7.5 to 15 and now to 25mg.weekly now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works.i'm not expecting it to work over night but soon hopefullyi am still in so much pain everyday and hoping for some relieve soon. Hydroxychloroquine immunosuppressant Plaquenil heart rate Take good care of your mouth to help prevent mouth sores. Use a soft toothbrush and a mouthwash. Avoid drinking alcohol or keep alcohol intake to a minimum while taking methotrexate. If you are a woman with child-bearing potential, you should always use a reliable form of contraception while you are taking methotrexate. Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. (others may do) and i then can get benefits till i find a job i can do with the ra(i am not doing this just for benefits, i hope people understand that) I have now been on Plaq for just over three years and MTX for just under three years. Also had to have an occupational health meeting today for my job as not worked for 6 months now and hoping they make me redundant as i can't work as a waitress with ra due to pain and flares in my opinion. Why take hydroxychloroquine with methotrexate Methotrexate Managing Side Effects Arthritis Foundation, Methotrexate vs Plaquenil Comparison - How does plaquenil treat rheumatoid arthritisPlaquenil false positivePlaquenil therapy for sjogrens icd 10Plaquenil heart Methotrexate is a drug used for rheumatoid arthritis, psoriasis and inflammatory bowel disease. It is taken on just one day a week. Accidental daily dosing can cause life-threatening toxicity. Weekly Dose methotrexate, the anti-inflammatory drug that.. Hydroxychloroquine Plaquenil. How to Lose Weight While on Methotrexate Hello Motherhood. The most common side effects are fatigue a day or two after you take methotrexate, which is why I suggest taking it at night,” he says. “Also gastrointestinal issues. Your stool may be loose, or you may feel queasy or nauseated for a day or two after. Ask your doctor if it’s OK to take methotrexate and folic acid on the same day, because there's no one-size-fits-all guideline. Always make sure you take methotrexate exactly as prescribed, and watch out for side effects. Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset.