In fact, most people with lupus have fatigue at some point in their illness. “When lupus hit, it was like running into a wall at 80 mph,” says Ann S. Is calcium citrate and plaquenil Drug category for hydroxychloroquine Chloroquine phosphate synthesis Days plaquenil to work Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. I've never heard of anyone having fatigue from plaquenil since I've been on these forums. Usually, auto immune diseases and the conditions that go with them such as anemia and vitamin deficiencies cause the fatigue. Fatigue is a very common complaint among those living with lupus. HSS Rheumatologist, Dr. Jessica Berman indicates that research estimates 40% of lupus patients have persistent severe fatigue, meaning that the fatigue stays for a long period of time. “I had been very active my whole life, and the fatigue just knocked me flat. Utterback, Ph D, a broadcast voice specialist in Virginia who was diagnosed with lupus in 2006. Plaquenil and extreme fatigue Plaquenil and Depression/Anxiety - Symptoms and Medical., Is extreme fatigue a side effect of Plaquenil? Plaquenil breastfeeding categoryWhat is hydroxychloroquine sulfate 200 mg used for Since one third of lupus individuals have fibromyalgia, it is no surprise that extreme fatigue comes with it. Severe pain, anemia, kidney dysfunction, thyroid issues, immune suppression and adrenal fatigue are other physical conditions that can cause lupus fatigue, as well. LUPUS FATIGUE Symptoms and Treatment - Kaleidoscope.. Patient Information on Lupus Fatigue HSS Rheumatology. Ask the Expert Plaquenil and Sjögren’s. I too suffer from extreme fatigue and have been unable to work since September 2008. I have been on plaquenil for several years and have seen great results as far as the joint pain goes I also have Rheumatoid Arthritis. Fatigue induced by other physical conditions 8. Fatigue related to other physical causes, such as thyroid problems or anemia superimposed on Sjögren’s. This kind of fatigue makes you feel that you are climbing a steep hill when you are really walking on level ground. It resolves once the underlying organic condition is diagnosed and treated. Please I need to find out if anyone who has taken plaquenil has experienced back and hip pain. I started in Oct of 2011 taking 200 mg of plaquenil once a day. In April of 2012 I started taking 400 mg 2 x's a day. I did start to notice that I was having pain when I tried to sleep at night. Mostly in my arms hands and ankles.