Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Synthesis of chloroquine from m-chloroaniline What do plaquenil pills look like Hydroxychloroquine cardiomyopathy Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Learn about the wide-ranging effects of hydroxychloroquine Plaquenil® in the treatment of lupus dosing, benefits, side effects and rare complications of this commonly prescribed medication. To reduce stomach upset, HCQ is best taken with food or milk. Benefits. Severe stomach pains, back pain, etc. Upper Stomach Pain, Nausea & Burning of the Stomach swollen feet and plaquenil bad stomach pains Keppra and stomach/abdominal pain Stomach pain from Fasomax Constant Stomach Pain. Stomach discomfort with diarrhea and gurgling of stomach Severe stomach pain, unexplained chronic nausea, any side effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil stomach upset Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Drug spotlight on hydroxychloroquine Lupus Foundation of. Can plaquenil cause depressionPlaquenil and infection riskChloroquine phosphate buy I am on Plaquenil and it makes my stomach hurt. I take a lot of Tums and make sure I eat when I take my meds. Also, Plaquenil is hard on the eyes to some people so get them checked and tell your eye doctor you are on it and that you have RA. Good luck. I've been on plaquenil for about 14 years and have not had any problems with it. Plaquenil Arthritis Information. Stomach pain from using plaquenil Undiagnosed Abdominal Pain.. Hydroxychloroquine Side Effects Common, Severe, Long Term.. COMMON BRAND NAMES Plaquenil. Uses. This medication is used to treat rheumatoid arthritis and lupus; and to treat or prevent malaria. How To Use. Take this medication with food to prevent stomach upset. Take this medication exactly as prescribed. Do not stop taking it without consulting your doctor. I suspect plaquenil for giving me some episodic diarrhea. I am 100 mg dose and take it with my supper. Did they happen to anyone else and did it eventually stop with the diarrhea side effect? It helps so much with the fatigue and pain. I have a sensitive stomach and perhaps I shouldn't have eaten that salad for lunch yesterday. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can.