Please review the following URL and make sure that it is spelled correctly. I have been on the plaquenil 200 mgm for about 4 months now. Hydroxychloroquine and azithromycin Ra plaquenil Hydroxychloroquine Plaquenil was originally used to treat malaria and is now used mostly to treat rheumatological and dermatological diseases. Its most frequent use now is for Rheumatoid Arthritis RA and Lupus and is often very effective in mitigating the joint and arthritic symptoms these. The Rheumatology nurse on the helpline suggested I stop it altogether until I could be seen. When I saw the Rheumatologist he refused to put me back on it and said the pain and fatigue I am now feeling is just Fibromyalgia as the Hydroxychloroquine takes 8 months to wear off so if I am getting symptoms it is not Lupus related. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. Symptoms coming off plaquenil Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., Coming off hydroxychloroquine-- symptoms returning? - LUPUS UK Carbamazepine interaction hydroxychloroquineHow does plaquenil fight malaria Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease Hydroxychloroquine toxicity - EyeWiki. What is the correct way to discontinue use of plaquenil?. Stopping Plaquenil - General Discussion - Life With Lupus. Are there other risks from long term plaquenil use? I have very mild RA and the plaquenil has kept symptoms in check. I have been off the drug two times and RA symptoms come on after about 3-4 weeks. I don't want to go to the next level of treatment as I am doing well on plaquenil and Celebrex. Thanks, XXXXXXX [email protected] Within a week most of them said that their symptoms came back with a vengence. for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Glad all of your tests have come back normal. Common side effects Nausea and diarrhea This can often can be combatted by taking Plaquenil with food or milk. Dizziness Precautions with this side effect Do not drive, use machinery. Cramps. Headache. Dry skin. Loss of appetite.