MTX monotherapy (MTG) is recommended as (part of) first choice treatment but no head-to-head comparisons are available comparing MTX–HCQ CTG with MTG. RA patients from the Sint Maartenskliniek and Radboudumc Nijmegen who started MTX with or without concomitant HCQ from April 2010 to October 2015 were included. Difference chloroquine bafilomycin a1 Effects of chloroquine on the liver Plaquenil and your eyes What does plaquenil help MTX vs Plaquenil. April 5. From what I read so far, seems like methotrexate is a bigger drug with more side effects so plaquenil would be the better choice. Any. Compare Hydroxychloroquine vs. Methotrexate, which is better for uses like RA, Lupus and Arthritis. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Interaction between Methotrexate and Plaquenil There is no known interaction between Methotrexate and Plaquenil in our records. However, an interaction may still exist. Always consult your doctor before taking these medications toget Regression modelling was used to correct for confounding. The primary outcome was the between-group ΔDAS28-CRP at 6 months, and secondary outcomes were ΔDAS28-CRP at 12 months, EULAR response at 6 and 12 months, and treatment intensification. Methotrexate vs plaquenil Methotrexate vs Plaquenil Comparison -, Compare Hydroxychloroquine vs Methotrexate - Comprehensive. Plaquenil lupus medication With Plaquenil, the possibility of permanent vision damage scares me. I also want to be sure that I'm taking a drug that will slow/stop the progression of the disease. I've read elsewhere that Plaquenil is not as strong/effective in the treatment of early RA. With Methotrexate, the reports of nausea and possible liver damage are concerning. Plaquenil vs Methotrexate rheumatoid - reddit. Compare Methotrexate vs Plaquenil for Lupus - Comprehensive.. Effects of methotrexate and hydroxychloroquine combination.. You just helped educate me. Thanks. I always thought that plaquenil was not a DMARD, but never bothered to look. I do know that plaquenil is generally considered the least invasive drug, generally prescribed as the first line of treatment. Methotrexate is the most commonly prescribed DMARD, but it does come with the chance of side-effects. I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Thanks I haven't had any issues with Plaquenil, and I've been on it for 13 years. Be sure you get your eyes checked regularly for Plaquenil toxicity, a very rare side effect that can affect your vision, but is usually reversible if caught early. I know Plaquenil has helped me a ton, because I tried going off of it once to see if I really needed it.