Note: based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. It is one of very few available drugs that inhibits autophagy, a mechanism associated with its anticancer properties. Plaquenil maculopathy oct images Synthesis of chloroquine phosphate slideshare Lupus and breast cancer. Some data indicate that women with lupus experience an increased risk of breast cancer. Increased estrogen levels might contribute to a higher risk of breast cancer in women with lupus. Lupus and lung cancer. Lung cancer is about 1.4 times more common in people with lupus than in the general population. I've been taking Plaquenil for a couple of years now with no issues. I started taking Tamoxifen about a month ago. I've noticed that my eyes have been bothering me more and more, especially in the last couple of days. I feel like I can't see clearly, like there's something in my eyes all the time. Indeed, current clinical trials are trying to use chloroquine or hydroxychloroquine, alone or in combination with other drugs to inhibit autophagy during breast cancer therapy since chemotherapy and radiation, regimens that are used to treat breast cancer, are known to induce autophagy in cancer cells. In cancer, authophagy is the process used by cancer cells to “self-eat” in order to survive. Specifically, if authophagy is prolonged this will become a lethal process to cancer. duing chemotheraphy, radiotheraphy, etc.) authophagy is used by cancer cells to survive. However, note that Chloroquine has other properties as well that may be very well related to anti cancer mechanism, such as zinc ionophore, and others (see below the section on mechanisms). Can plaquenil cause breast cancer Bad Side Effects of Plaquenil -, Breast Cancer Topic Tamoxifen plus Plaquenil anyone? Eye. Chloroquine for lung cancer In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Chloroquine & Hydroxychloroquine supporting chemo.. Did You Know This About Arthritis and Cancer Risk?. Plaquenil can cause irreversible damage to the retina back of the eye where vision is formed. It is very important to have an eye exam before taking Plaquenil and then follow-up as needed while taking the drug. Are taking Tamoxifen medicine to treat breast cancer. Both Plaquenil and Tamoxifen can individually cause damage to retina. I'm a breast cancer survivor and am concerned about taking prednisone for fear of recurrence? Asked by sativ Updated 12 December 2009 Topics breast cancer, cancer, prednisone Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow, tapering off, and if you have a reaction, severe fatigue, etc, talk to your doc, about tapering down even slower.