One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Chloroquine lysosome sigma Generic drug for plaquenil Chloroquine volume of distribution Severe blood disorder such as aplastic anemia, agranulocytosis, leukopenia, or thrombocytopenia, appears which is not attributable to the disease under treatment, consider discontinuation of PLAQUENIL. Show Full Comment Comment This medication relieved my joint pain, muscle weakness, myositis, pleuritic pain, and fatigue after about 2-3 months of starting the medication. Full-field ERGs were performed only in selected patients to evaluate the extent of damage beyond the macula. Patient E3 showed reduced cone amplitude in 1 eye only that was of doubtful significance because the flicker response times to peak were normal and symmetrical. Patients M3 and M4 had normal full-field ERG findings. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil ful fielderg severe Plaquenil Side Effects Common, Severe, Long Term -, Plaquenil oral Reviews and User Ratings Effectiveness, Ease. What family of drugs does chloroquine belong toHydroxychloroquine flu vaccineChloroquine phosphate and alcoholChloroquine autophagy fluxBisoprolol and hydroxychloroquine Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Multimodal Imaging in Plaquenil Toxicity. Comparison of Screening Procedures in Hydroxychloroquine Toxicity. Plaquenil hydroxychloroquine sulfate dose, indications.. Worsening of psoriasis and porphyria Use of PLAQUENIL in patients with psoriasis may precipitate a severe attack of psoriasis. When used in patients with porphyria the condition may be exacerbated. When used in patients with porphyria the condition may be exacerbated. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. And, as far as Plaquenil and eye problems, the Ophthamologists I've talked to including a Neuro Ophthalmologist say that while Plaquenil can cause serious damage to the optic nerve, it's very rare. Annual appointments with an ophthalmologist are important in order to catch any problems early.