While the mechanism is poorly understood, pregnant women have a reduced immune response and therefore less effectively clear malaria infections. In addition, malaria parasites sequester and replicate in the placenta. What drugs interact with plaquenil Blue cross plaquenil tier If you use other drugs or over the counter products at the same time, the effects of Chloroquine Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Controlled studies evaluating the safety and efficacy of chloroquine in pregnant women. Usage of chloroquine during pregnancy should be avoided except in the suppression or treatment of malaria when in the judgment of the physician the benefit outweighs the potential risk to the fetus. PRECAUTIONS Hematological Effects/Laboratory Tests Pregnancies exposed to quinine or chloroquine and carried to term did not have increased rates of congenital abnormality, stillbirth or low birthweight. These results suggest that therapeutic doses of quinine and chloroquine are safe to use in the first trimester of pregnancy. Keywords malaria, Plasmodium falciparum. Malaria infection during pregnancy can lead to miscarriage, premature delivery, low birth weight, congenital infection, and/or perinatal death. Pregnant women are three times more likely to develop severe disease than non-pregnant women acquiring infections from the same area. Effect of chloroquine injection on early pregnancy Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs, ASW-2F ARALEN® CHLOROQUINE PHOSPHATE, USP Hydroxychloroquin cardiac protectiveHydroxychloroquine diagnostic studiesDoes hydroxychloroquine make you bone painPara que es plaquenil Chloroquine is an antimalarial medication which is used in the treatment as well as prophylaxis of malaria. This medicine is not recommended in patients with the eye disease. Liver function and blood cell count monitoring is necessary while receiving this medicine. Chloroquine - Uses, Dosage, Side Effects, Composition.. The effects of quinine and chloroquine antimalarial.. Chloroquine Indications, Side Effects, Warnings -. Chloroquine has not been formally assigned to a pregnancy category by the FDA. There are no controlled data in human pregnancies. Congenital anomalies were reported in the offspring of one woman being treated with chloroquine 250 to 500 mg daily during pregnancy for SLE; however, chloroquine has been used in the prophylaxis and treatment of malaria during pregnancy without evidence of fetal harm. The only times that progesterone levels differ are during the luteal phase of a woman's menstrual cycle and during pregnancy. During pregnancy, progesterone plays an important role, especially early in the first trimester. This is when the hormone is responsible for helping "prep" the uterus for the fertilized embryo. Malaria during pregnancy has adverse effects, including maternal mortality, miscarriage, and low birthweight. During early pregnancy, treatment options are limited, especially in regions with drug resistance. In a retrospective study covering a 25-year period 1986–2010.