Diseases associated with lupus can cause these oral symptoms, and the side-effects of lupus medications can appear in the oral cavity as well. Although the disease does not directly target teeth, lupus and teeth problems frequently occur together. Chloroquine diphsophate How does h-chloroquine work for rheumatoid arthritis Plaquenil side effects mouth sores Feb 16, 2016 Lupus can cause dry mouth leading to tooth issues. And often Lupus is accompanied by a secondary disorder, Sjogren's Syndrome, which also causes dry mouth leading to tooth decay. I don't think the Plaquenil or the Prednisone are causing the issue -- you should check in with your rheumatologist. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. African American and Asian women are most at risk of developing the condition. Lupus According to the University of Maryland Medical Center, lupus is known medically as systemic lupus erythematosus, an autoimmune disease that results in chronic inflammation. Plaquenil and teeth Dental Concerns - Lupus International, Common and Rare Side Effects for Plaquenil Oral Antacid and plaquenilDoes hydroxychloroquine cause weight lossPlaquenil and flu Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil Uses, Dosage & Side Effects -. Long-Term Side Effects of Plaquenil for Rheumatoid.. Starting an osteoporosis drug? Here's what you need to know.. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. Plaquenil is also used in some circumstances to control arthritis and may result in a lichenoid reaction or rash on the inside of the mouth. Immunosuppressive medications such as cyclophosphamide or methotrexate may result in opportunistic bacterial infection which could compromise periodontaly involved teeth or dental implants.