One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Can use of plaquenil have effect on vaccinations years later Chloroquine lc3b Plaquenil maculopathy report How long do hydroxychloroquine side effects last Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Feb 19, 2020 Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have Your ophthalmologist may use these tests to look for retina damage from Plaquenil Visual field test During this test you sit down and look into a bowl-like machine. OCT imaging This test makes a detailed, three-dimensional image of your eye. Multifocal ERG This test looks at cells in the. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil retina damage Hydroxychloroquine-Induced Retinal Toxicity - American., Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Chloroquine fas associatedChloroquine resistance in indiaHalf life of hydroxychloroquine sulfate Hydroxychloroquine has significantly less retinal toxicity and has largely replaced chloroquine as a treatment of inflammatory disease. Unfortunately, the retinal damage from these medications is largely irreversible, so it is critical to detect early retinal toxicity in the hopes of limiting the extent of visual loss. Sign/Symptoms Hydroxychloroquine Plaquenil Toxicity and Recommendations.. How Do Ophthalmologists Look for Plaquenil Damage.. Long-Term Side Effects of Plaquenil for Rheumatoid.. In particular, chloroquine and hydroxychloroquine Plaquenil are two such medications, with the potential for retinal toxicity. Given that the retinal damage from these medications is largely irreversible, screening by a retinal specialist is critical to detect early retinal toxicity to try and limit the extent of visual loss. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Feb 19, 2020 PLAQUENIL is not effective against chloroquine-resistant strains of P. falciparum see CLINICAL PHARMACOLOGY - Microbiology. Ocular. Irreversible retinal damage has been observed in some patients who had received hydroxychloroquine sulfate.