There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by incidence or effect, said Frederick W. “Rick” Fraunfelder, MD, director of the Registry and associate professor of ophthalmology at Oregon Health & Science University in Portland. Plaquenil retina Plaquenil dose toxicity Cardiomyopathy caused by plaquenil Hydroxychloroquine renal toxicity Plaquenil decreases Botox efficacy. Detailed Answer Hi, I have gone through your question and understand your concerns. Caution should be taken if Botox is injected after Plaquenil use, because Plaquenil reduces efficacy of Botox and itching at injection site are reported. There is no absolute contraindication in using both these drugs. Botox and other variations is a toxin which limits the nerve signals which cause eye muscles to go into spasm. It is used as a cosmetic agent to stop forehead facial muscles from contracting and forming wrinkles in the skin. Botulinum toxin treatment was originally introduced to treat muscle spasms, including blepharospasm spasms of the eyelids, strabismus squint, cervical dystonia torticollis of the neck and spasticity due to cerebral palsy or other muscular diseases. In patients treated for facial spasms. “It’s a pretty rare thing.” Nevertheless, he urged doctors to master the Academy’s new guidelines, because the effects from chloroquine and hydroxychloroquine, when they do occur, are severe and often irreversible. “Plaquenil toxicity isn’t even in the top 10, or the top 100” if you’re looking at incidence, he said. Plaquenil and botox Let me tell you what weaning down from Plaquenil is like., Sjogrens and Botox Hi all Has anyone. - The Australian. Chloroquine phosphate invertsIs a side effect of hydroxychloroquine making my cheeks flushChloroquine torsades While rare, complications do occur with the esthetic use of dermal fillers. Careful attention to patient factors and technique can do much to avoid these complications, and a well-informed practitioner can mitigate problems when they do occur. Since cosmetic. Patient factors influencing dermal filler complications.. Botulinum toxin DermNet NZ. Drugs & Medications That Can Trigger Psoriasis Flare-Ups. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Botox itself is a muscle relaxer made from bacteria. It’s been on the market for over two decades, and has been used to treat neurological disorders that cause muscle weakness. Hydroxychloroquine Plaquenil, a drug designed to treat malaria, is often helpful in treating Sjogren's syndrome. Drugs that suppress the immune system, such as methotrexate Trexall, also might be prescribed. Surgery. A minor procedure to seal the tear ducts that drain tears from your eyes punctal occlusion might help relieve your dry eyes.