Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). Plaquenil effect on heart 98 hydroxychloroquine Chloroquine egfr Nov 25, 2019 Initial dose 400 mg 310 mg base orally 1 to 2 times a day; this dose may be continued for several weeks or months, depending on patient response Maintenance dose 200 to 400 mg 155 to 310 mg base orally daily Comments-Each dose should be taken with a meal or a glass of milk. Hydroxychloroquine retinopathy is most influenced by daily dose and duration of use. Risk for toxicity is less with 5.0 mg/kg real weight/day for hydroxychloroquine and 2.3 mg/kg real weight/day for chloroquine. Patients are at low risk during the first 5 years of treatment. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. As one can see, the height that corresponds to an ideal body weight of 135 pounds varies across the formulas. It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. Hydroxychloroquine dose by weight Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Hydroxychloroquine toxicity - EyeWiki Chloroquine combination therapyPlaquenil lower plateltlsHydroxychloroquine treats what conditions Summary Weight loss is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 2-9 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Juvenile rheumatoid arthritis. Will you have Weight loss with Hydroxychloroquine sulfate.. Ideal Body Weight for Calculating Hydroxychloroquine Dosage.. Plaquenil hydroxychloroquine sulfate dosing, indications.. Let's dive in. Melton & Thomas describe the typical safe Plaquenil dosage this way The usual dosage is two 200mg tablets per day. This is generally a "safe" dose for patients having a lean body weight of at least 135 lbs. The generally-regarded safe dosage is 6.5mg/kg/qd, thus the 135 lb. safety threshold. The weekly dosage for adults is 310mg base 400mg salt. Your doctor will have calculated the correct weekly dose for your child based on the child’s weight. The child’s dose should not exceed the adult dose of. 310mg base 400mg salt per week. Where can I buy. hydroxychloroquine? Antimalarial drugs are available in the United States Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage.