Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil side effects anti depressants Hydroxychloroquine photosensitivity rash Plaquenil comes in 200 mg tablets, and many doctors just off-handedly put everyone on 200 mg twice a day. Other risk factors, such as underlying maculopathy, renal disease and use of. Plaquenil increases the pH of lysosomes and impairs complement-dependent antigen-antibody reactions. It also inhibits the chemotaxis of eosinophils and locomotion of neutrophils. SUMMARY OF EVIDENCE in development Ponticelli C et al. 2017 “Hydroxychloroquine in systemic lupus erythematosus SLE” Expert Opin Drug Saf. Mar; 163411-419. Renal clearance in rheumatoid arthritis RA patients taking PLAQUENIL for at least six months seemed to be similar to that of the single dose studies in volunteers, suggesting that no change occurs with chronic dosing. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil creatinine Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Hydroxychloroquine Plaquenil RheumTutor Can i take plaquenil and adipex togetherSanofi aventis plaquenil PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of P. vivax and P. malariae infections, concomitant therapy with an 8-aminoquinoline compound is necessary. Plaquenil Dosage Guide -. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. High Creatinine Symptoms What May Occur When Your Levels Are Off. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Because renal clearance of hydroxychloroquine does not correlate with creatinine clearance, dosage adjustments are not required in patients with renal impairment. However, a dosage reduction may be necessary in patients with renal disease or in patients with concomitant medications known to affect the kidney. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days.