Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Hydroxychloroquine and seizure meds Chloroquine trade name Hydroxychloroquine and nerve damage Chloroquine is an inhibitor of the lysosomal degradation of the DNA which is taken up by the cells, so as leelee said, transfection should have been successful, albeit at a slightly lower level than if you would have added the chloroquine. In my normal transfections, I never add chloroquine and get high efficiencies nevertheless. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin. Chloroquine, a medication used to prevent and to treat malaria, has just been confirmed as one of the three anti-viral drug for Coronavirus. The search for the cure of Coronavirus has been on for some time The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine diphosphate use Aquarium Fish Chloroquine A "New" Drug for Treating Fish., Chloroquine phosphate C18H32ClN3O8P2 - PubChem Hydroxychloroquine metabolismDo you have to wean off hydroxychloroquine Sasaki et al 2010 Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells. BMC Cancer 10 370 PMID 20630104. If you know of a relevant reference for Chloroquine diphosphate, please let us know. Chloroquine diphosphate Supplier CAS 50-63-5 Tocris Bioscience. Chloroquine confirmed as anti-viral drug for Coronavirus. Chloroquine - Wikipedia. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors TLRs. Chloroquine diphosphate is an antimalarial and anti-inflammatory drug widely used to treat malaria and rheumatoid arthritis. - Mechanism of Action & Protocol. Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. The anti-malarial agent chloroquine diphosphate, which is also used to treat immunological, dermatological, and rheumatological disorders, usually causes pigmentary changes in the oral mucosa. This report presents a case of palate pigmentation related to the prolonged use of chloroquine diphosphate caused by the deposition of drug metabolites.