I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Chloroquine phosphate effects on fish Arthritis medicine plaquenil I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. What happens if I miss a dose Plaquenil, Plaquenil Sulfate, Quineprox? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose Plaquenil, Plaquenil Sulfate, Quineprox? If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few months, but it can take up to six months for full effects. Stop taking the medicine and. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. What will happen if i stop taking plaquenil Treating Lupus with Anti-Malarial Drugs Johns Hopkins., Plaquenil Hydroxychloroquine Side effects, Images, Uses. Plaquenil sjorensPlaquenil rheumatoid arthritis renalHydroxychloroquine 300 mgHydroxychloroquine copay assistanceChloroquine phosphate for malaria It's ok to stop plaquenil without weaning, but I do recommend that if you feel you can wait til Monday, wait, and talk with your rheumy then. I felt that plaquenil wasn't helping, and was causing digestive problems for me, so with my dr. ok, I went off it. After two weeks off, I discovered it had been doing some good on the joint and muscle pain. Can you quit plaquenil cold turkey, or have to wean. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Don't want to take plaquenil anymore - HealthBoards. I just had major spine surgery in November. The surgeon had me check with my rheumy about stopping Plaquenil and I was told to continue it, or just stop it the day of surgery then get right back on, I asked what would happen if I stopped for a week and was told I'd risk going into a flare. I stayed on it and surgery went OK. I can't believe you were told to stop taking plaquenil after only 6 months since it can take up to one YEAR to achieve full benefits! I don't know much about any sort of withdrawal but if I were you I'd start taking it again. I'd also have your thyroid checked. I'm hypothyroid and take levo along with he plaquenil. What happens if I stop taking plaquenil hydroxychloroquine suddenly? Dr. John Goldman, University of Cincinnati College of Medicine Answered Aug. 28, 2012 54 years experience in Internal Medicine - Rheumatology Long time. Plaquenil hydroxychloroquine takes a long time to get out of the system - up to 18 months. Be certain you and your.