Plaquenil and diabetic retinopathy

Discussion in 'Without A Doctor Prescription' started by -BRAIN-, 26-Feb-2020.

  1. 3newz Well-Known Member

    Plaquenil and diabetic retinopathy


    She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation.

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    A study of 12 patients with hydroxychloroquine retinopathy and 103 patients being treated with hydroxychloroquine but without retinopathy reported a sensitivity of 85.7% for 10–2 VFA and 78.6% for SD-OCT, and specificities of 92.5% and 98.1%, respectively. The use of hydroxychloroquine is increasing, with an estimated 11,000 new treatment initiations per year in England and Wales. Modern retinal imaging techniques identify the prevalence of hydroxychloroquine retinopathy at around 7.5% in patients taking the drug for more than 5 years, increasing to 20% to 50% after 20 years. Diabetic retinopathy develops in people with type 1 or type 2 diabetes. It takes years to develop. Two kinds of diabetic retinopathy have the potential to diminish vision In nonproliferative retinopathy, blood vessels in the retina deteriorate. Deteriorating blood vessels can become blocked or deformed.

    Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use.

    Plaquenil and diabetic retinopathy

    How to Succeed in Plaquenil Screenings, Screening and Management of Hydroxychloroquine Retinopathy.

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  4. Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease

    • Hydroxychloroquine toxicity - EyeWiki.
    • Retinopathy Guide Causes, Symptoms and Treatment Options.
    • Hydroxychloroquine blood levels predict retinopathy risk..

    Hydroxychloroquine HCQ is an antimalarial agent that is commonly used to treat rheumatoid arthritis RA and systemic lupus erythematosus SLE. The present report documents a case of hypoglycaemia due to HCQ in a patient with SLE and diabetes mellitus type 2, in which the HCQ completely replaced the need for daily subcutaneous insulin. If you are using Plaquenil, The Wellish Vision Institute recommends regular eye exams to help catch any change that may be subtly occurring. Symptoms of retinopathy to be aware of are blind spots in your central vision, distortion of objects, blurring, light flashes and sensitivity, as well as colors becoming distorted and difficulty seeing at night. Hydroxychloroquine and Chloroquine Retinopathy is the first single-source book on the subject and is essential for the practicing ophthalmologists, rheumatologists, dermatologists, and internists who prescribe these drugs. It covers clinical topics such as signs and symptoms of toxicity, toxicity screening, ancillary testing, to whom and why the drugs are prescribed and dosing considerations.

     
  5. Xedos Guest

    To ensure the safety of both patients and donors, these are some of the requirements donors must meet to be eligible to donate blood based on their donation type. Study Finds Blood Levels of Plaquenil may be Important. Plaquenil - Donating Blood & Platelets Medications That May Delay.
     
  6. forever_young XenForo Moderator

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  7. saintist New Member

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    Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus
     
  8. korzhkov Moderator

    Hydroxychloroquine sulfate and Methotrexate drug interactions. Summary Drug interactions are reported among people who take Hydroxychloroquine sulfate and Methotrexate together. This study is created by eHealthMe based on reports of 5,663 people who take Hydroxychloroquine sulfate and Methotrexate from Food and Drug Administration FDA, and is updated regularly.

    Effects of methotrexate and hydroxychloroquine combination.