Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Desethyl hydroxychloroquine Synthesis of chloroquine from m chloroaniline How quickly does damage from plaquenil Agranulocytosis is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Multiple myeloma Autoimmune neutropenia, caused by neutrophil-specific autoantibodies is a common phenomenon in autoimmune disorders such as Felty's syndrome and systemic lupus erythematosus. Felty's syndrome is associated with neutropenia and splenomegaly in seropositive rheumatoid arthritis which can be severe and with recurrent bacterial infections. Bel neutropenia low white cell count can be an autoimmune condition in and of itself. Those of use with AIs often develop several and gain more over time. Neutropenia is something to be concerned about as low counts leave you very vulnerable to infection. I know because I have neutropenia and my hematologist tracks my neutrophils carefully. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil autoimmune neutropenia Plaquenil - FDA prescribing information, side effects and uses, Management of autoimmune neutropenia in Felty's syndrome. Areas of chloroquine resistant malariaPlaquenil bleedingStarting plaquenil during pregnancy Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed. Taking Plaquenil for Rheumatoid Arthritis. Link between low white cell count and taking Plaquenil?. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine HCQ is frequently used to treat autoimmune diseases, especially systemic lupus erythematosus SLE. Although its exact mechanism of action in autoimmune diseases is not completely understood, we do know that HCQ has many benefits and plays a key role in the management of many diseases. WebMD discusses the symptoms, causes, and treatment of neutropenia, an immune system condition that may lead to infections. Plaquenil tablets contain the active ingredient hydroxychloroquine, which is a type of medicine called a disease-modifying anti-rheumatic drug DMARD. It is used to treat rheumatoid arthritis.