A, At the start of hydroxychloroquine sulfate treatment. B, Two years after starting treatment, a right paracentral scotoma appeared. Plaquenil and meningitis Chloroquine iupac name A, Visual field 10-2, showing a white pattern deviation plot above a red gray-scale plot. B, A multifocal electroretinography mfERG trace array showing broad maculopathy and a clear ring of weak signals between the fovea and the more peripheral regions. Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Either modality showed clear losses in moderate retinopathy. On repeated testing, the pattern deviation plots were somewhat more consistent than red fields in showing parafoveal damage. Conclusions With white 10-2 visual field hydroxychloroquine screening, the use of pattern deviation plots should be standard practice. Red testing appears to be more sensitive for early retinopathy but may be slightly less specific or consistent. Morand EFMc Cloud PILittlejohn GO Continuation of long term treatment with hydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis. C, Three years after cessation of treatment, the scotoma regressed. Plaquenil visual field red stimulus Humphrey visual field findings in hydroxychloroquine toxicity, Recommendations on Screening for Chloroquine and Hydroxychloroquine. Rash with hydroxychloroquineDoes plaquenil cause blindnessCan plaquenil be used in the treatment of multiple myeloma Jan 01, 2020 The molecular weight of hydroxychloroquine sulfate is 433.95, and molecular formula is C 18 H 26 ClN 3 O. H 2 SO 4. Plaquenil hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Inactive Ingredients Dibasic calcium phosphate USP. Plaquenil - FDA prescribing information, side effects and uses. Value of Red Targets and Pattern Deviation Plots in Visual.. Dots, Squiggles, and Triangles, Oh My! A Visual Field Guide.. Diagnosis of a toxic reaction was based on assessment of visual field findings according to the criteria outlined by Bernstein, 3 where acceptance of a case as a valid retinopathy requires as a minimum the presence and persistence of central or paracentral visual field scotomas to suprathreshold white stimuli and a duration of treatment of at least 9 months with a daily dose of hydroxychloroquine sulfate of 400 mg or less. Figure 3 Five consecutive 10-2 visual fields VFs with a white target. Notes VFs of a patient taking hydroxychloroquine at toxic doses who developed retinopathy. An incomplete annular scotoma in the zone from 2 to 8 degrees from fixation developed in the third VF. The AAO recommends that all patients beginning hydroxychloroquine therapy have a baseline evaluation, including a complete dilated examination and visual field test Amsler grid or Humphrey 10-2 perimetry. Other testing, such as color vision and fundus photography, is optional.