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    It is the most widely used method of birth control in the world. It has been estimated that nearly 1 in 4 pregnancies are terminated, many illegally. "Back-street" and self-induced abortions are still present - worldwide they cause 30-50% of all maternal deaths from pregnancy and childbirth. There has been a gradual liberalization of laws, and today well over 75% of the world's population live in countries where abortion is to a greater or lesser extent legal. The limit varies from 20 to 24 weeks in various countries. With the improvement of childbirth, this figure may be even higher. The complications arise mainly from unhygienic and unskillful termination of pregnancy resulting in infection, injuries and hemorrhage. doxycycline 100 mg tab Furthermore, there is no legal requirement for parental consent for minors and there is no defined limitation on age according to the Singapore Termination of Pregnancy (To P) Act. The one caveat is if you are below 14 years of age – this is deemed to be statutory rape, and thus will have to be reported to your parents and the police. In addition, abortion services are not allowed for pregnancies beyond 24 weeks (6 months) unless there is the mother’s life is in danger or the fetus has a severe abnormality. In such cases, approval must be obtained from necessary authorities for the abortion to be conducted. Abortion services are usually only available to citizens of Singapore; however, foreigners may be eligible for abortion services if they meet at least one of the following conditions: Note: The Abortion Law act requires that the woman undergo brief counseling by a qualified abortion counselor at any accredited abortion clinic.

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    L’agence ADK-Kasting dispose d’une base de données de près de 3000 comédiens belges et internationaux, professionnels ou non. Vous aurez accès, sur ce site, à une galerie de plusieurs centaines de comédiens(nes), professionnel(le)s, non professionnel(le)s, enfants, adolescents ou adultes. Cette communauté riche et variée est le fruit de plusieurs années de castings sur plus d’une centaine de projets… Afin d’obtenir plus d’infos, ou si vous souhaitez avoir accès à l’ensemble de nos services, n’hésitez pas à envoyer un mail à [email protected] ADK-Kasting est en permanence à la recherche de talents. En vous inscrivant sur ce site, vous créez votre profil et le mettez à jour quand vous le souhaitez. Vous pouvez également ajouter des photos et extraits vidéos. étant régulièrement utilisé par des réalisateurs, vous augmentez ainsi vos chances de visibilité. I offer a personalized and experienced service which is safe, intimate, confidential and speedy. Abortion is a very traumatic and private procedure and what you do not want is to go through a very public hospital with lots of doctors and nurses, maybe even medical students seeing you go though this painful event in your life. I am been performing this procedure since the early 1980s, and therefore have more than 25 years’ experience in the field. I can confidently handle abortions up to 24 weeks in my clinic without the need for hospitalization. My clinic in Ang Mo Kio has been offering this uninterrupted service since the late 1980s. You can therefore be assured of reliable and experienced service. for example, you need to know how to look after yourself and your baby for a successful outcome.

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    Indicated to reduce the incidence of breast cancer in women at high risk for breast cancer; high risk is defined as women aged ≥35 years with a 5-year predicted risk of breast cancer ≥1.67% (calculated by the Gail Model) 20 mg PO q Day for 5 years Data are limited for use Hypersensitivity Pregnancy Undiagnosed vaginal bleeding Patients who require concomitant warfarin therapy or have a history of deep vein thrombosis or pulmonary embolus if indication for treatment is either reduction of breast cancer incidence in high-risk patients or risk reduction of invasive breast cancer after treatment of DCIS Liver cancer and changes in liver enzyme levels reported with use; on rare occasions, a spectrum of more severe liver abnormalities including fatty liver, cholestasis, hepatitis and hepatic necrosis, that have included fatalities, also reported; monitor liver function periodically Unknown whether an increased risk for other (non-uterine) cancers is associated with tamoxifen Hypercalcemia reported in some breast cancer patients with bone metastases within a few weeks of starting treatment; if hypercalcemia occurs, treat as appropriate; if hypercalcemia is severe, discontinue therapy CYP2D6 polymorphism-CYP2D6 converts tamoxifen to active metabolite endoxifen; lowered CYP2D6 activity or concomitant CYP2D6 inhibitors may reduce tamoxifen efficacy Decreases in platelet counts, usually to 50,000-100,000/mm3, infrequently lower, reported in patients receiving therapy for breast cancer; hemorrhagic episodes have occurred, but not certain if episodes were due to tamoxifen therapy; leukopenia, sometimes in association with anemia and/or thrombocytopenia reported; neutropenia and pancytopenia also reported; perform periodic complete blood counts, including platelet counts Ocular disturbances, including corneal changes, decrement in color vision perception, retinal vein thrombosis, and retinopathy reported; an increased incidence of cataracts and need for cataract surgery reported; patients should seek medical attention if they experience visual disturbance There is increased incidence of thromboembolic events, including deep vein thrombosis and pulmonary embolism, during tamoxifen therapy; when tamoxifen is coadministered with chemotherapy, there is further increase in risk of thromboembolic events; for treatment of breast cancer, carefully consider risks and benefits of tamoxifen in women with a history of thromboembolic events; advise patients to seek medical attention immediately if signs or symptoms of a thromboembolic event occur Increased incidence of uterine malignancies (endometrial adenocarcinoma and uterine sarcoma), including fatal cases, reported with treatment; underlying mechanism unknown, most uterine malignancies seen with tamoxifen are classified as adenocarcinoma of the endometrium; however, uterine sarcomas, including malignant mixed mullerian tumors (MMMT), generally associated with a higher FIGO stage (III/IV), also reported; uterine sarcoma at diagnosis usually associated with poor prognosis, and short survival; uterine sarcoma reported to occur more frequently among long-term users (≥2 years) of tamoxifen than non-users; promptly evaluate patient receiving or who has previously received therapy who reports abnormal vaginal bleeding; patients receiving or who have previously received tamoxifen should have annual gynecological examinations Therapy can cause fetal harm when administered to pregnant woman; there are postmarketing reports of vaginal bleeding, spontaneous abortions, birth defects, and fetal deaths in pregnant women taking tamoxifen; in primate model, administration of drug at doses 2 times maximum recommended human dose resulted in spontaneous abortion; advise pregnant women of potential risks to a fetus, including potential long-term risk of a DES-like syndrome; advise females of reproductive potential to use effective non-hormonal contraception during treatment with tamoxifen and for 9 months following the last dose Fetal harm may occur when administered to a pregnant woman There are postmarketing reports of vaginal bleeding, spontaneous abortions, birth defects, and fetal deaths in pregnant women taking tamoxifen In a primate model, administration of tamoxifen at doses 2 times the maximum recommended human dose resulted in spontaneous abortion Advise pregnant women of potential risks to a fetus, including potential long term risk of a DES-like syndrome Prior to initiating treatment, a negative pregnancy test should be confirmed Tamoxifen reported to inhibit lactation Two placebo-controlled studies in over 150 women have shown that tamoxifen significantly inhibits early postpartum milk production; both studies tamoxifen was administered within 24 hr of delivery for between 5 and 18 days; effect of tamoxifen on established milk production is not known There are no data that address whether tamoxifen is excreted into human milk; direct neonatal exposure of tamoxifen to mice and rats (not via breast milk) produced 1) reproductive tract lesions in female rodents (similar to those seen in humans after intrauterine exposure to diethylstilbestrol) and 2) functional defects of the reproductive tract in male rodents such as testicular atrophy and arrest of spermatogenesis Unknown if tamoxifen is excreted in human milk Because of potential for serious adverse reactions in nursing infants from tamoxifen, women taking tamoxifen should not breast feed Selective estrogen receptor modulator: nonsteroid with potent antiestrogenic effects in breast (but may be estrogen agonist in uterus); has cytostatic effect rather than cytocidal effects (cells accumulate in Go and G1 phase of the cell cycle) Half-Life: 7-14 hr Peak Plasma Time: 3-6 hr Protein binding: 99% Peak Plasma Concentration: 40 ng/m L Metabolism: by hepatic P450 enzyme CYP2C9, CYP2D6, CYP3A4 Metabolites: N-desmethyl tamoxifen, endoxifen Excretion: Feces (65%), urine (9%) Metabolized via CYP2D6 into endoxifen (4-OH-N-desmethyl-tamoxifen), its primary active metabolite Lowered CYP2D6 activity or concomitant CYP2D6 inhibitors may reduce tamoxifen efficacy Poor CYP2D6 metabolizers are defined as those with *4/*4 alleles On October 18, 2006, the Pharmaceutical Science Clinical Pharmacology Subcommittee of the FDA recommended including information on CYP2D6 genotypes and their potential effect on patient outcomes in the label for tamoxifen, but they did not come to consensus on whether testing should be recommended or considered optional Subsequent to that recommendation, branded tamoxifen (Nolvadex) was discontinued and no further guidance was given by FDA on whether to amend the label for generic tamoxifen Recent data presented at the 2010 San Antonio Breast Cancer Symposium found the CYP2D6 allele status had no effect on any outcomes, including disease recurrence, distant recurrence, and overall survival Further research will help elucidate the potential effect of strong CYP2D6 inhibitors, such as SSRIs, on tamoxifen metabolism, but there is no evidence to suggest that the use of such medications should influence the use of tamoxifen Therefore, based on the data available to date, routine testing for CYP2D6 variants is not recommended CYP2C19 heterozygous *2 carriership may be a predictive factor for patients with breast cancer using tamoxifen; this factor was associated with a longer survival among tamoxifen users in a recent study (Pharmacogenomics. 2010;11[10]:1367-75) The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. Tamoxifen - Side-effects - TabletWise metoprolol overdose treatment Jill Goodacre Is Stopping Tamoxifen What to Know About the Drug. Tamoxifen Side Effects in Women - Imaginis
     
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    As many as 25 percent of people who take certain antidepressant medications report gaining weight, and sometimes quite a bit – as much as 100 pounds. some of the drugs that may be least likely to lead to weight gain are Effexor (venlafaxine) and Serzone (nafazodone), while Wellbutrin (bupropion) tends to cause weight loss. Most antidepressants can cause weight gain, and different drugs affect individuals differently- you may gain weight on one antidepressant but not on another, even if the second is known to cause weight gain in some individuals. Conversely, he says that one of the antidepressants that seems most likely to cause weight gain is Paxil, an SSRI (selective serotonin reuptake inhibitor). Overall, it’s believed the effect is more likely to occur after taking medication for six months or longer. Of the other SSRIs, which include Prozac, Lexapro and Celexa, Zoloft may be least likely to cause weight gain. Some may trigger food cravings, particularly for carbohydrates. It is also possible that when the antidepressants are effective, you become less depressed and regain your appetite (though this would only apply in cases where loss of appetite is a symptom of depression). And bear in mind that overeating can also be a symptom of depression that can cause weight gain regardless of taking antidepressants. In the midst of the obesity epidemic, unwanted weight gain due to antidepressant use is rarely mentioned, although it could be a significant contributor since these drugs are now the most commonly prescribed pharmaceuticals in the United States. In 2005 (the last year for which figures are available) some 27 million Americans age six and older were taking January 6, 2010 concluded that prescription anti-depressants may provide little benefit for patients with mild or moderate depression although they do help patients with very severe depression. Here are my recommendations for treating mild to moderate depression. Duloxetine & Gabapentin – Weight Gain / Weight Loss - can you buy generic lexapro How Cymbalta Is Associated With Weight Gain Antidepressants That Cause Weight Gain
     
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