Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality. Drugwatch partners with Physicians’ Review Network Inc. PRN is a nationally recognized leader in providing independent medical reviews. Reviewer specialties include internal medicine, gastroenterology, oncology, orthopedic surgery and psychiatry. Zithromax (azithromycin), also known as Z-Pak, is an antibiotic approved for treatment of respiratory, skin and other bacterial infections. Food and Drug Administration warned of an increased risk of cancer relapse and death in some patients who take the drug long-term. Studies link the drug to side effects, including an increased risk of fatal heart problems. Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality. Drugwatch partners with Physicians’ Review Network Inc. PRN is a nationally recognized leader in providing independent medical reviews. Reviewer specialties include internal medicine, gastroenterology, oncology, orthopedic surgery and psychiatry. doxycycline before and after Zithromax (azithromycin) is an antibiotic that fights bacteria. Zithromax is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. Zithromax may also be used for purposes not listed in this medication guide. You should not use Zithromax if you have ever had jaundice or liver problems caused by taking azithromycin. You should not use Zithromax if you are allergic to azithromycin, or if: Zithromax is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether azithromycin passes into breast milk or if it could harm a nursing baby. Do not give Zithromax to a child younger than 6 months old. 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